It’s 1970s Dublin and eighteen-year-old Brianna Robinson is determined to become a nurse. Her mother is equally determined to stop her. When Brianna secretly travels to London for an interview to train in a major hospital, there’s a family furore. A deal is struck with her parish priest and Brianna will train in Dublin.

At the nursing college, Brianna befriends three other girls. They are assigned to midwifery in the slums of Dublin, where they discover untold poverty. Contraception is illegal in the Republic of Ireland, it is both a criminal offence and a mortal sin. At the hospital ball she discovers a wolf lurks in the background.

While moonlighting at a private midwifery practice a catastrophe occurs and she tries to escape from Dublin. Her friends travel with her to the North of Ireland on The Belfast Express.

Despite “The Troubles”, they enjoy a wild weekend in Belfast. Amid the heady fashions and music, Brianna’s quest forges new friendships leading to chaos at Dublin’s Connolly railway station.

In the spirit of Call the Midwife, The Belfast Express shows how brave young women celebrate friendship, courage and - through a bizarre and colourful defiance - stand up to the Catholic Church and the Irish Government.